Sexual dimorphism in 137Cs accumulation after chronic low dose exposure in mice | Scientific Reports - Nature

A recent study published in *Scientific Reports* investigates the effects of chronic low-dose exposure to Cesium-137 (137Cs) on male and female mice. The research highlights significant differences in 137Cs biodistribution and dosimetry between sexes after exposure through drinking water, simulating scenarios similar to those faced by populations near nuclear accident sites like Chernobyl and Fukushima. Male mice exhibited a higher body burden of 137Cs, with significant accumulation in skeletal muscle, while female mice showed more efficient elimination of the isotope, particularly through urine. The absorbed doses were also found to be significantly higher in males than females, indicating a need for gender-specific considerations in radiation protection policies. This study suggests that biological responses to radioactive contamination may differ between sexes and underlines the importance of further research into sex-specific health risks associated with internal contamination.

Mon, 03 Nov 2025 10:04:44 GMT | Nature